Conferència “Els fons europeus a Catalunya: oportunitats i eines de creixement”. Presentació del nou portal del Govern #FonsUECat ; i que impartirà el Sr. Amadeu Altafaj i Tardio, representant permanent del Govern de la Generalitat davant la Unió Europea.
Es demana confirmació d’assistència a protocol.girona@gencat.cat
A càrrec de Laura M. Lechuga del Nanobiosensors and Bioanalytical Applications Group Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC, The Barcelona Institute of Science and Technology and CIBER-BBN Barcelona (Spain)
Abstract
The need to monitor and detect biological elements, related to human and environment health in a fast and reliable way, is one of the challenges faced by humanity at the dawn of the 21st century. Tests done nowadays in laboratories (as ELISA, PCRs, cell cultures, etc.) are slow (from several hours to days) and expensive. Modern diagnostics is demanding novel analytical tools that could enable quick, accurate, sensitive, reliable and cost-effective results so that appropriate treatments can be implemented in time, leading to improved outcomes. Such portable point-of-care (POC) devices, able to deliver an instant diagnostics, could become a reality soon thanks to the last advances in nanobiosensors, lab-on-a-chip, wireless and portable technologies which promise to surpass the existing challenges, opening the door to a global diagnostics access.
The driving force of our research is to achieve such ultrasensitive platforms for POC label-free analysis using nanophotonic technologies and custom-designed biofunctionalization protocols, accomplishing the requirements of disposability and portability. We are using innovative designs of nanophotonic biosensors based on silicon photonics technology (nanointerferometers) and full microfluidics lab-on-chip integration. We employ dedicated biofunctionalization routes of the biological receptors (as proteins or genomic strands) ensuring selectivity, life-cycle, non-fouling properties and reusability.
Moreover, we have demonstrated the applicability of our biosensor technology for real life requests, mainly for clinical diagnostics (i.e early cancer diagnostics), and for environmental control, with extremely sensitivity and selectivity, of marine pollutants directly using untreated sea water, microbiological infections and toxins.
A càrrec de Laura M. Lechuga del Nanobiosensors and Bioanalytical Applications Group Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC, The Barcelona Institute of Science and Technology and CIBER-BBN Barcelona (Spain)
Abstract
The need to monitor and detect biological elements, related to human and environment health in a fast and reliable way, is one of the challenges faced by humanity at the dawn of the 21st century. Tests done nowadays in laboratories (as ELISA, PCRs, cell cultures, etc.) are slow (from several hours to days) and expensive. Modern diagnostics is demanding novel analytical tools that could enable quick, accurate, sensitive, reliable and cost-effective results so that appropriate treatments can be implemented in time, leading to improved outcomes. Such portable point-of-care (POC) devices, able to deliver an instant diagnostics, could become a reality soon thanks to the last advances in nanobiosensors, lab-on-a-chip, wireless and portable technologies which promise to surpass the existing challenges, opening the door to a global diagnostics access.
The driving force of our research is to achieve such ultrasensitive platforms for POC label-free analysis using nanophotonic technologies and custom-designed biofunctionalization protocols, accomplishing the requirements of disposability and portability. We are using innovative designs of nanophotonic biosensors based on silicon photonics technology (nanointerferometers) and full microfluidics lab-on-chip integration. We employ dedicated biofunctionalization routes of the biological receptors (as proteins or genomic strands) ensuring selectivity, life-cycle, non-fouling properties and reusability.
Moreover, we have demonstrated the applicability of our biosensor technology for real life requests, mainly for clinical diagnostics (i.e early cancer diagnostics), and for environmental control, with extremely sensitivity and selectivity, of marine pollutants directly using untreated sea water, microbiological infections and toxins.
Dades del curs:
Objectiu:
Continguts:
"La informació que ofereix aquest web i els continguts tal com apareixen poden contenir errors. No ens fem responsables d'errors tipogràfics, tècnics, canvis en informació, preus, etcètera. No oferim cap tipus de garantia, implícita o explícita, sobre la informació aquí exposada, imatges, o qualsevol altre tipus de dret o llicència d'aquest acord”
L’ICRA us convida al seminari “Exploiting Nanotechnology and Nature to build novel materials” a càrrec de la Dr. Anna Laromaine del grup de nanopartícules i nanocompòsits; ICMAB-CSIC, Campus UAB, Bellaterra. www.icmab.es/nn
The need to provide eco-friendly materials to reduce costs and risks associated to waste echoes in many fields as the European Commission strengthens the substitution of plastics and petroleum-based materials. In this context, raw materials of natural origin and in particular natural biopolymers like cellulose play an important role. Cellulose (C) and nanocellulose (NC)-based materials have emerged as interesting candidates to industries, governments and consumers as green, sustainable and natural materials for the fabrication of advanced complex composites.
Additionally nanoparticles (NPs) offer the possibility to chemically and structurally tune their properties influencing how they interact with different materials. Hundreds of NPs have been proposed in a diverse fields, however the lack of a time- and batch-efficient method to evaluate NPs and processes prevents establishing general fundamental principles and impedes their progress, in specific as future drugs and therapies unless high throughput methods advance.
The possibility to combine materials of raw origin, like cellulose, with nanoparticles open new avenues in the development of novel materials, which harness nanotechnology and nature.
In this context, we will present our latest development on novel stimuli responsive materials for a variety of applications. In addition, we will show how we can evaluate those biomaterials on the in vivo Caenorhabditis elegans, which emerges as a test-bed for the multiparametric optimization of those nanomaterials.
BIO
Anna Laromaine is a chemist from the University of Girona (UdG), PhD in Chemistry from the Materials Science Institute of Barcelona (ICMAB) and the Autonomous University of Barcelona (UAB) with extensive international scientific experience. Her PhD focused on the molecular synthesis of carboranes for catalysis and medical therapy. As postdoctoral researcher at Imperial College London (UK) in the group of Prof. Molly M. Stevens, she developed a colorimetric sensor for the detection of proteases based on gold nanoparticles and peptides. She studied the replication of surfaces with DNA and peptides using supramolecular interactions at MIT (USA) in the group of Prof. Francesco Stellacci. They developed new methodologies for the production of cell cultures in three-dimensional structures on paper and the combination of the use of C. elegans and microfluidic chips for innovative biological assays at Harvard University (USA) in the group of Prof. George Whitesides.
She is currently Investigadora Distinguida at the ICMAB where she combines materials science, chemistry and biology for biological applications. She focuses on the use of cellulose materials and nanoparticles to create multifunctional composites and responsive material. The interaction of those novel materials is evaluated in cells within 2D and 3D cell cultures and using the animal C. elegans. They optimize the physico-chemical properties of the novel multifunctional materials using biocompatible approaches that are economical and have low environmental impact.
She actively participates and has experience in scientific divulgation activities and technology transfer.